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The risk of cardiovascular disease is still significantly increased in patients with inflammatory arthritis. This is the conclusion reached by researchers at Amsterdam UMC RMD opened.
The study included 2050 patients with inflammatory arthritis (IA) and 939 controls, including 1308 patients with rheumatoid arthritis (RA), 356 patients with psoriatic arthritis (PsA) and 386 patients with axial spondyloarthritis (SpA).
They were asked to complete questionnaires about previous cardiovascular events and various risk factors in a prospective cohort setting. The researchers then assessed the prevalence of cardiovascular disease and associated risk factors.
Traditional cardiovascular risk factors were found to be more common in patients with IA than in controls. The risk of cardiovascular disease was also higher in patients with RA and PsA than in controls; 1.61 and 2.12 times higher, respectively.
The increased risk appears to be strongly influenced by an increased prevalence of traditional cardiovascular risk factors. After adjustment, cardiovascular risk did not appear to be increased in patients with RA (OR 0.95), PsA (OR 1.19) and SpA (OR 0.91). According to the authors, more attention should therefore be paid to identifying and treating traditional risk factors.
Bron:
Raadsen R, Hansildaar R, Pouw LC, et al. The risk of cardiovascular disease is still significantly increased in patients with inflammatory arthritis today. RMD opened. 2023;9:e003485.
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