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According to The Times, a medical study conducted in the Netherlands and Britain found that the likelihood of developing dementia before the age of 65 depends not only on genes but also on health and lifestyle factors. Researchers have found a variety of risk factors for people who develop dementia symptoms before age 65.
A large-scale study by teams of researchers found that genes can significantly increase the risk of early-onset dementia, as can a range of environmental and lifestyle factors, including lower education and alcohol abuse.
According to the Alzheimer’s Society, more than 70,800 people in the UK have early-onset dementia, accounting for around 8% of all dementia sufferers. The results challenge the idea that genetics is the sole cause of this disease and pave the way for new prevention strategies.
Dr. Janice Ranson, senior researcher at the University of Exeter, told The Times: “Our research breaks new ground in determining whether the risk of early dementia can be reduced.” We believe this is a new era of interventions to reduce new dementia could herald cases of this disease.”
The study, published in the journal JAMA Neurology, was conducted by researchers at the University of Exeter and Maastricht University in the Netherlands. More than 350,000 people under the age of 65 were tracked in the UK.
The study found 15 risk factors, including hearing impairment, heart disease, social isolation and lower socioeconomic status.
David Llewellyn, a professor at the University of Exeter, said the research was “the largest and most powerful study of its kind ever conducted” and involved big data analysis and international collaboration.
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