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Doing sports – Corona (expressive)
Al Arabiya.net – Jamal Nazi
Published on: January 20, 2024: 08:38 am GST. Last updated: January 20, 2024: 08:38 AM GST
One of the most common symptoms of long-term COVID-19 illness is a tendency to engage in strenuous exercise, which worsens the condition.
Not only does the long-term coronavirus effect reduce a person’s physical performance, but more widespread symptoms often appear in the days following exercise sessions. Researchers have called this phenomenon “post-exertional malaise” (PEM), and it is a relatively strange phenomenon.
Physiological explanations and basics
According to the New Atlas website, citing two studies whose results were published in the journals ERJ Open Research and Nature Communications, exercise is beneficial in most rehabilitation cases, and when a patient suffers from exercise, there are usually clear Physiological Symptoms Explanations: The heart or lungs may not be functioning properly, or a long period of illness may have resulted in a type of physical deconditioning in which the body is generally weakened.
But in many cases of long-term COVID-19, there are no clear signs that explain movement restrictions. Many patients have been bombarded with traditional tests only to be told they are perfectly fine, but several new studies are beginning to unravel the mystery behind a long period of infection. With the corona virus.
Although the results do not immediately point to solutions, they confirm that cases of persistent exercise intolerance related to the coronavirus have physiological underpinnings.
Corona Covid lungs emoji
Cardiopulmonary exercise test
The most traditional test of a patient’s functional physical performance is called the cardiopulmonary exercise test (CPET). The patient is placed on an exercise bike while doctors monitor heart rate, oxygen saturation and electrocardiogram data.
For many long-term coronavirus patients, CPET exams produce unusually normal results. Despite obvious limitations with exercise, such as shortness of breath, these patients often have normal oxygen levels and healthy heart function.
Calisthenics – iStock
Invasive cardiopulmonary training
A team of researchers at Yale University conducted a study on a group of long-term coronavirus patients that included a new CPET study, known as iCPET, or invasive cardiopulmonary exercise test, which is more complex than a regular CPET test. In addition to regular CPET procedures, patients undergoing this test have two pressure-sensing catheters inserted into their arteries, providing an additional look at the effects of exercise on muscles and blood vessels.
Systemic oxygen extraction
The results were astonishing, showing no noticeable problems in heart or lung function, but showing significant abnormalities in the way the body’s tissues absorb oxygen. The dysfunction was classified as impaired systemic oxygen extraction pEO2.
Peter Khan, the study’s lead researcher, explained that they found that “despite the fact that the heart pumps oxygenated blood, which is supplied with sufficient oxygen by the lungs, extracting oxygen from the body’s tissues causes symptoms in patients.” showed, was impaired.” the exercise intolerance.” Sport after Covid. However, it could not be assumed exactly why or how this happened, as researchers suggested several possible explanations for this unusual phenomenon.
The study’s researchers speculate that “impaired pEO2 may be due to an inability of the vascular beds to adequately constrict vasoconstriction or direct muscle blood flow outside of exercise, or to inadequate capillary diffusion to mitochondria.”
Interesting evidence
A study recently published in the journal Nature Communications by a team of scientists at the University of Amsterdam provides interesting clues about what could happen. The answer seems to have something to do with mitochondria, the tiny power plants that provide energy to individual cells.
The unique study from the University of Amsterdam included a group of long-term coronavirus patients and a healthy control group. Study participants completed a strenuous cycling test and provided blood and muscle tissue samples one week before and one day after the test.
Abnormalities in muscle tissue
Rob West, a researcher involved in the study, said poor metabolism and signs of significant muscle damage were found in Covid patients over a long period of time after strenuous exercise. Perhaps most importantly, the results showed that strenuous exercise actually caused mitochondrial dysfunction in muscle cells, which could explain why Long Covid patients feel worse the day after exercise.
“We saw different abnormalities in the muscle tissue of the patients. At the cellular level, we saw that the mitochondria in the muscles, also called the cell’s energy factories, were functioning less well and producing less energy from the cells,” explains Foust.
Morning exercises – iStock
Mitochondrial dysfunction
To date, mitochondrial dysfunction has been suggested as a possible explanation for some of the long-term symptoms of the coronavirus, but how exactly SARS-CoV-2 infection causes mitochondrial dysfunction remains a mystery. Although exercise is always considered beneficial for mitochondrial function, the rule does not apply to patients with diabetes, Foust noted [كوفيد طويل الأمد]. Apparently, muscle damage and the resulting infiltration of immune cells can also affect mitochondrial function
Mild physical exertion
Brent Appleman, co-investigator of the Amsterdam study, says long-term Covid patients should be careful not to push themselves beyond their limits. It is now becoming increasingly clear that excessive effort is harmful, and the reason for this is only partially understood.
“Specifically, these patients can be counseled,” says Appleman [المتعافين من كوفيد طويل الأمد] By respecting and not exceeding their physical limits, since they can undertake light efforts that do not aggravate the discomfort,” noting that “Walking is a good thing or riding an electric bike to improve health and a certain physical fitness maintain, and both.” Man must remember that what is suitable for others may be stressful for him.”
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