Science | AAAS

Speech clocks decode dementia phenotypes, social exposome, and biological aging

NIH details $170 million biomedical research reproducibility effort

Transposable elements as evolutionary catalysts of ant macrodiversity

Escape of the BC200 gene to a human poxvirus reveals its persistent transposition in primates

Mammals produce cyclo -octasulfur to suppress lipid peroxidation and ferroptosis

2D theoretically twistable material database

Dogs Have a 'Consonant Bias'

Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program

Targeting an atypical G protein–coupled receptor signaling pathway for cardiac fibrosis therapy

A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas

This dolphin chased a fish until it puked—then ate the vomit

Noise and diversity can boost stability

Protecting tropical forests is more cost-effective for biodiversity and climate than restoration

The Virtual Biotech: A multi-agent AI framework for therapeutic discovery and development

Germline EGFR T790M mutation and lung cancer risk

OpenAI breakthrough triggers ‘existential crisis’ in math

Pangaea’s ‘little brother’ may finally qualify as a supercontinent

In situ structure of the human ciliary transition zone links linker defects to primary ciliary dyskinesia

Extensive and differential platinum chemotherapy mutagenesis in livers of children

Chronic type II interferon promotes tumor growth through mitochondrial RNA–induced type I interferon and prostaglandin synthesis

Closed-loop auditory stimulation in phase with slow waves during sleep enhances cerebrospinal fluid flow in humans

Oligoclonal nanobody-based recombinant antivenom protects mice challenged with venom from cobras and king cobras from India

Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species

Three thousand five hundred years of sheeppox virus evolution inferred from archaeological and codicological genomes

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Observation of the quantum phase of free fall and the consistency with the equivalence principle

Early-life colonization with Clostridioides difficile remodels the developing gut

Longitudinal dynamics of gene expression and metabolomics in an aging population cohort

(Un)intended consequences of mass-prescribing GLP-1s

Psilocybin May Prevent Nerve Damage Caused by Chemotherapy, Study Finds

NASA’s New Horizons mission may shut down two instruments over lack of funding

Snake embryos often coil in one direction. Now, we may know why

This is what a Jurassic forest may have sounded like

Kyle Hamilton Explains Why the Danger of Football Is a Sacrifice He Accepts

Reconstructed Jurassic insect calls evoke a 165-million-year-old forest soundscape

Tracking the baryon number with nuclear collisions

‘Mismatched’ vaccine being rolled out against Ebola outbreak

The microenvironment dictates glyco-immune surveillance via HSF1-mediated metabolism

Birdsong similar to human language, study finds

Tau protein can sneak into brain cells’ energy factories—and wreak havoc

Fossil evidence favors a role for vision in the modular evolution of the primate neocortex

A central role for dietary sugars in human evolution

Adaptive modulation of theta sweeps in the brain’s navigation circuit

With lucky dive, scientists get a front-row view of the creation of Earth’s surface

A 10-million-year biogeographic holding pen primed the Great American Biotic Interchange

Recovering signatures of archaic hominin introgression using ancestral recombination graphs

Girl’s undisclosed death in gene-editing trial raises red flags in booming Chinese industry

Highly aquatic marine stem archosaur with soft tissue preservation

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Genetic diversity of late Neanderthals in northwestern Europe