« We don’t have enough perspective. This is one of the arguments most advanced by those who are reluctant to get vaccinated. Can possible illnesses or serious side effects really occur months or even years after the injection?

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[EN VIDÉO] How does a messenger RNA vaccine work?
Pfizer and Moderna have chosen this cutting-edge technique to design their vaccine against Covid-19 in record time. This video presents everything you need to know about messenger RNA vaccines in three minutes!

« According to a 2011 study, drug safety risks appear on average 4 years after their approval […] We will put young people and adolescents at potential risk and mortgage their future », Warns thelawyer from Didier Raoult, Fabrice Di Vizio, notoriously opposed to “vaccine tyranny.” The study mentioned by the lawyer, published in 2017 and covering 222 drugs approved by the FDA shows that a third of drugs cause side effects not reported during clinical tests (especially psychotropic drugs). But these effects remain very limited, barely three drugs having been finally withdrawn from the market.

In addition, there is a big difference between a medicine and a vaccine: in the former case, the medicine is taken continuously, which means that the doses accumulate in the body. We know for example that, when they are taken for more than three months continuously, corticosteroids may cause swelling of the face or upper body, weakening of the muscles or skin. A vaccine is only injected once or twice; this danger of accumulation therefore does not exist.

Long-term effects with other vaccines were still seen, right?

In 1998, a study had made the link between the vaccine ROR (measles, mumps, rubella) and autism. Study of just 12 children and retracted since, but which continued to sow doubt among antivax. During the 1990s, other studies explored a possible link between the vaccine againstHepatitis B and the risk of autoimmune disease such as multiple sclerosis. A suspicion which even led the public authorities to suspend the vaccination in schools in 1998 (while maintaining compulsory vaccination of infants and health professionals). But finally, no solid proof could ever be brought to this link.

There are of course very rare cases of vaccination-related disorders, such as those of AstraZeneca vaccine-related thrombosis, but they appear a few days after the injection. Given the very careful pharmacovigilance on vaccines anti-Covid, a side effect is unlikely to have passed under the radar of health authorities.

Yes, but messenger RNA vaccines are a new technology that has never been tested?

Even though the technology MRNA has more than 20 years of research behind it, it is true that this is the first time that it has been used for vaccination against an infectious disease. However, it is biologically almost impossible that it can induce long-term effects. Indeed, RNA vaccines globally contain two active ingredients (besides water and salt): the lipid capsule used to transport mRNA in the cell, and the strand ofARN messenger himself. However, these two elements are quickly eliminated by the body: the lipid capsule dissolves in the body to release mRNA and the latter, which is very fragile, is also destroyed within a few hours. In other words, if these ingredients presented a danger, its effects would manifest itself within hours or days of the injection. No risk of modifying the genome. « In any case, the injected RNA does not penetrate into the nucleus of the cells where the genetic material is located. », reminds Inserm.

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