In particular, one of the studies shows that there is no risk of miscarriage or premature birth with messenger RNA vaccines.
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Reassuring conclusions. Messenger RNA Covid vaccines pose little risk to pregnant women, according to two recent studies. One of them shows in particular that there is no particular danger of miscarriage or premature birth.
The first, published on August 12 in the Lancet Infectious Diseases, evaluate the immediate risks of side effects in pregnant women after a messenger RNA vaccine. The second, published Thursday August 18 in the British Medical Journal (BMJ) measures long-term risks during childbirth.
Both studies offer reassuring conclusions about these vaccines, one developed by Pfizer/BioNTech and the other by Moderna, which form the core of anti-Covid vaccination in several countries such as France. “Covid-19 vaccination during pregnancy is not associated with a higher risk of preterm birth [ou] of miscarriage”summarize the BMJ authors, and also conclude that there is no danger that the newborn will be abnormally small.
This work, conducted in Canada, retrospectively studied more than 85,000 births or miscarriages that occurred between May and December 2021. In approximately half of the cases, the mother received one or two doses of the Covid vaccine – mostly messenger RNA – during her pregnancy. Ultimately, the outcome of pregnancy is no different in this group.
As for the immediate side effects of messenger RNA vaccines, they are usually less frequent during pregnancy, according to the study of the Lancet Infectious Diseases. The authors compared the data from more than 5,000 women who were vaccinated during their pregnancy with that of about 300 pregnant and unvaccinated women.