# Alnylam’s heart drug troubles take center stage at a cardiology conference

> **Newsylist Open Intelligence Dossier** · First detected: 2026-08-28 13:29 UTC · Category: Business · Sources: 8 · Current Velocity: 7.78

## Multi-Source Evidence Table
| Source Outlet | Headline | Published (UTC) | Verification URL |
|---|---|---|---|
| Investing.com | Why is Alnylam Pharmaceuticals stock sliding today? | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMisgFBVV95cUxNSk1oN3o3VzdoOFRFajhiVDlMNWgtemhlNFZLdmVNbmF4RU9pQ3l0TlN5LUhWTTkwZGZMeTh3aGdFbWFMLWZvZTNBUnBXMDdqa04yNVBwQlQxaW9qa1FoQ0F3MVZPV1NjTTZTUXdfY0lzdG5VWXpCRmdEX2FmTXU5dFpMaUhJSHVCZlhMWEtTZS1SZG1IclA3N0Z1Zms3bWMxUVRBYzJBUUtyS1FwVjk3N2Rn?oc=5) |
| Investing.com | Alnylam stock drops on rival heart trial: Why analysts see core business safe | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMizgFBVV95cUxPN2dTNGU3ejJlMlVpOHYtQlV1X3Y5bXAyUDl2Y09XWFBCVnNpRXdsTzRzSGlWS2l1c2NaYUg2U0kwU1F1RDNSa21CSGllZzVORm1FOHkwcDZWcEFVcThWa1pMcWMyS0RkRGdEN3VmT2FiWGJlM2JleGpSNG9iejdNdWwxRVA2c3FkbGFoNnpkUXc4dXpCVjZpZmhxMkN0cGFmQlV1M1pqR3VmZzVOZGh3cTROR3RRVGxYRUFqbGMzODZXNUpqZWVCd2thOTk3dw?oc=5) |
| BioPharma Dive | AstraZeneca, Ionis data spark debate about RNA drugs’ impact on deadly heart disease | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMipgFBVV95cUxOY054bjdxaFV5eDB2dWtBN2FGNkVGN3JReGc5cEFwWmVHM1B2djRnNTZtaHBfS2YyMFFVVDk1OXBuQm9adFgtQWVWbF83MXB4R29UWUs5TGhrNmNkNy11TnZnVGRWQ1VNUDVUVWJlOTVFd2tGWGFHYkNnOHh5S3hkNFRqU1c4R3l4cGNSbEdOYmZaaEVlZ2Q2cFUtcjRJU3I0VVRWSlln?oc=5) |
| BioSpace | ‘Worse than expected’ Wainua data muddies water for TTR silencers | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMiqAFBVV95cUxPNnh6bU1xc1g2R3JFVVVCRnpiRFJaYWdMbXVqZm9KbzlYRm1FQXRCNWZ0OFdzTk1EZHJFYjRUNFJ3b1lrcTZscjRtT0p6X1B0MjFZNXlyak00WHJ1YkdWb3dHd2szc1FCblRaZGFtZzJlNFEzeGsxU1dwYnBpZlJOYjNDbzFCOGU4SS16cFdmT2JlWW9MZ0NmaG1WQ1V6c3hpM2NFU1NZR3k?oc=5) |
| STAT | AstraZeneca and Ionis detail surprise failure of heart disease drug, with Alnylam closely watching | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMiswFBVV95cUxOcldhVnY2RDgtTzFMdFNqQ2FKYml2R3FkVmM2UU5tYTROa1hwNFpRdzlkRUM3MG9iYmg3N0FtUUJReE9HYmZ4TVFLZlVNaVkxTGdBQ1c2Y0pHWFBMUEVsZDh6R003WkkxMURBLVFKZzhTaXBhOXduckd2TmRTaklNWXdVdTFPbEpoTC13T1pnOEEwVW1nWmRNNGhCWmt5S0E4bmFOVFRLQzFhWFc5SGMtRG9ocw?oc=5) |
| News-Medical | CARDIO-TTRansform trial investigating eplontersen fails to meet primary efficacy endpoint | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMi0wFBVV95cUxPNHdmbURPTWVyUGFuTWFaS2V6dGFSc3lwWU0xd2lwUkQwcjR2ZGJMQ09JMTJ1bVlPYXpPMUV1NWJhTjNBR3g4OE9iZzVaenctOVl5ZHNzZ0c1dnp4VTVLT2F6YUVxb08zZkdNVkFYMmFiZ3h0STdQRUdjcno2SE5CM3RBbkIxSHIwdEFHVlExZWV2cTNvUUFHUVd0RGpscTdPYkJhR2VJaDFwS0VodC1TYjh2eGd1N01OUl81cURsNU5PWGhTUzVpRmlEUzJBTldpRUdZ?oc=5) |
| Yahoo Finance | Is Alnylam (ALNY) Turning Expanded HELIOS-B and Zilebesiran Data Into Durable Cardiovascular Leadership? | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMingFBVV95cUxNZlRaZHFVWWZaUWMtMDNXVktkVGt5Wm82MDA3bkhwRkxqMDE5b2VZUS02U1VLdGhPemotdHJ2ZzBBZThURGttb1h5TGdoSXI2ZDJQVDFxV2NENU1NQ3ZLRXYtaUUtR1drR2NqRHprcXlJY1MySjE4cWV2N0tsalZTM291TWN1REJ1MU5pNGVTLW5nTUZVbmZUa25ZM2pjdw?oc=5) |
| Seeking Alpha | Alnylam drops as Astra posts trial data for failed heart drug | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMilwFBVV95cUxQQUFQRmp0WmtZRy1jOVlyMlhDRFZmRnRLc3dmclNpMGlzNDY0OTg0RC1zNE5jd1pJWEVGSjk3MUdiTGMtMnFrSG1oYmh0bV8yY05hNnFhMGpRMVpJbGVSckNuc25BaDFNTGc0eGY2aFRUcTRCV2JjWHQyX3V5a3p2SmhXekN3TG9wLTJyYjNzMDBGOXlSWVUw?oc=5) |
| Endpoints News | Future of AstraZeneca’s gene silencer in heart disease uncertain after trial failure | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMiowFBVV95cUxPakNrZmpLTy1pbFJHRUdtMU8yV29JWDNoUlROUWtidE50Uk1uQkVDaWkxMWVaMUs5MGxfVDctWWxqSE8zbExuNGtybEM3QW1QamJaeG9QNXVuY2dJQU45LWhTdFM3cDNHZ0hPVkVPMXRmNmx1b3FUNjZSUDJMSXl3aTlZM1JZenJKbktjSHhic1MxNWs1Z21jbHBKNlRWSGphYU00?oc=5) |
| STAT | In autopsy of failed heart disease study, AstraZeneca raises broader questions about silencer drugs | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMiswFBVV95cUxNSEE2dFdPQWRSY1g4dVROU283TjFpNUY1UEtYU0VabWVmRkZxYTg1NkJ0aF9vOHdSOS1EZFJnVU10X3RTa1l1dVNGQ2dQS3BEMHMzSHFiVXVpTnhIVTNZTGdfeTNrZ0wxNnZzMXpxZV9ZdUgwWFgycGFYX1FVZ2xLVmhuUVhFUU01bVZ4dFg1YzN4NmVtUUNVc0tBVzljMHFQVGx6YkRsWWJfdEtVaUJINXgySQ?oc=5) |
| STAT | Alnylam’s heart drug troubles take center stage at a cardiology conference | 2026-08-27 10:32 | [Source Link](https://news.google.com/rss/articles/CBMihwFBVV95cUxQQ2VzMjJUM2gyZU5GYmhkY2c1Y011WmczcVRjZktxNmlKSjI4WW12Xy0tR3ZId2QwVmt2SmJtQmozMW1jTU1EX3B0ZnEwT01kOFJueWFzY2RBNUFLYmZnOGZYMWszbFRKT242VVJ4NmgzUUZydFltVlNkTDZ6WVpEOWhzOTZqOU0?oc=5) |

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*Canonical Source: https://www.newsylist.com/trend/2026-08-28/alnylam-s-heart-drug-troubles-take-center-stage-at-a-cardiology-conference*
*Synthesized by Newsylist Open Intelligence Engine under E-E-A-T journalistic standards.*