- Uric acid level too high: How is the acid formed in the body?
- Too much uric acid can wristsbut also vessels and organs damage
- medication against gout
- Avoid purine-rich foods: tips on how to avoid the proper nutrition can lower the uric acid in the body
uric acid is a breakdown product that our body produces every day. The uric acid concentration is measured in the blood serum and should not exceed certain reference values. In addition to urea and creatinine, uric acid belongs to the so-called urinary substanceswhich must be excreted in the urine. They are therefore used as markers for kidney health. at increased values Various causes come into consideration, which result in inflammatory reactions, such as gout, but can also cause kidney and ureteral stones. In addition to genetic causes or other diseases, the food choices one of the main causes of too much uric acid in the body. who determined Eliminate food from the menu and eat a balanced diet can be Lowers uric acid levels permanently.
How is uric acid formed in the body?
Uric acid is formed during the breakdown of Purines. It is part of every cell and necessary for the genetic material and the construction of new cells. Above here purine foods such as high-fat meat, certain types of fish or high-sugar fruits, we absorb additional purines, which the body must also metabolize. The consumption of Fructose (fructose) is increasingly becoming the focus of researchers. Because fructose is added to many products in the food industry, for example in the form of corn starch, for example when soft drinks are sweetened. But also at Breakdown of the body’s own cells accumulate purines. This is especially the case with chemotherapy.
Also has uric acid positive effects and is important for protection against free radicals. She acts here as Antioxidant, protects against free radicals and has a tissue-protective effect. From the so-called Hyperuricemia experts say when the uric acid concentration in the blood serum rises above 6.7 mg/dl in women and 7.4 mg/dl in men. There are two different forms:
- Primary hyperuricemia: This is one genetic disorder, which can affect both uric acid formation and uric acid excretion. Certain enzymes important for uric acid metabolism work only to a limited extent.
- Secondary hyperuricemia: Come here various diseases or consequences of medication under consideration. Blood formation disorders, blood cancer (leukemia), kidney disease, alcoholism or dehydrating medications (diuretics) can promote an increase in uric acid concentration.
Too much uric acid can damage joints, but also blood vessels and organs
Too much uric acid in the body does not always lead to symptoms. However, if the uric acid concentration continuously exceed a certain limit, form uric acid crystals from which is found in body tissue deposit be able.
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gout belongs to the most common inflammatory joint diseases in Germany. At a acute gout attack the body tries to break down the uric acid crystals in the joint via an inflammatory response. The typical symptoms of inflammation then appear, such as overheating, swelling, redness and very severe pain. is common joints affectedwhich is far from the center of the body and has less blood supply. Typically, the first acute attacks of gout appear in the metatarsophalangeal joint, followed by the knee, elbow, wrist and finger joints. Coolness promotes the precipitation of uric acid crystals, as does low tissue pH. So can too infections and physical exertion cause a gout attack. Gout patients are typically male, overweight and suffer from high blood pressure, diabetes or kidney dysfunction.
Furthermore, there are many that point to too much uric acid as well Cardiovascular system and vessels can damage. Long before the first gout attack, the crystallizing uric acid can also development of kidney stones encourage and impede drainage.
medication for gout
Due to the massive inflammatory processes in the body, doctors see the need to do this Lowers uric acid levels permanently. According to the “S2 guideline on gouty arthritis”, in the case of an acute gout attack, the inflammation and pain must first be treated. The drug of choice in an acute gouty attack Colchicine, a naturally occurring substance from the poisonous plant autumn crocus. However, it is often difficult to find the dose, as symptoms of poisoning can occur under certain conditions.
After surviving a gout attack, with a long term therapy be started to prevent a chronic course. However, drug treatment is also included side effects connect so that a detailed exploration in a doctor-patient discussion significantly increases the success of the treatment.
Mostly so-called Uricostatic used, such as allopurinol or febuxostat. It inhibits an enzyme that reduces the formation of uric acid. There are also medications available that increases the excretion of uric acid (uricosurics) such as probenecid or benzbromarone.
Tips on how to lower the uric acid level in the body with the right diet
The upper limit of 500 milligrams of purines should not be exceeded daily. In acute gout attacks, a limit of 300 milligrams is recommended. A good overview of the uric acid content is provided by food table on goutinfo.de. So that the exposure to purines remains low, a diet change be very effective.
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Note the following tips:
1. Beware of vegetarian and alkaline excess foods Cost: The so-called DASH diet (Dietary Approaches to Stop Hypertension), which is based on a typical Mediterranean diet, is actually recommended for patients with high blood pressure and high cholesterol levels. However, a study was able to show that a reduction in uric acid levels is also achieved. In general, the following foods should be on your menu:
- Vegetables, sour cherries, berries
- Low-fat dairy products, especially yogurt, cottage cheese and hard cheese
- Bio owner
- cereal products or flakes
- Potatoes, egg noodles, rice
2. Avoid purine-rich foods: It is important that you not too many purines at once take to you For example, you should not combine high-fat meals with meat and alcohol. For example, it can be used as a guideline that in 150 grams of meat or chicken contains about half the amount of purines you should consume daily – about 210 milligrams. But smaller portions of meat can also be prepared tasty, for example as sliced meat. At the same time it helps removal of the skin saving a lot of purines in fish, meat or chicken, as well as avoiding high-fat sausages and offal. legumes and Soy products Contrary to earlier recommendations, however, they are in moderation (about 2x per week) harmless.
3. Skip the fructose: The fructose in fruit is usually unproblematic if the whole fruit is eaten. sour cherries is even attributed a uric acid-lowering effect. But also berry fruit is low in sugar. However, you should avoid dried fruit and agave syrup and especially ready-made products such as soft drinks, where Fructose as a sweetener is added. When fructose is broken down, uric acid is formed.
4. Drink enough: Two to three liters of water, unsweetened herbal and fruit teas and coffee are recommended. This allows uric acid to be excreted better. than is critical Alcohol to look at because it stimulates the formation of uric acid and at the same time inhibits excretion via the kidneys. Beer, which themselves contain purines, are considered the worst choice, even in the non-alcoholic version.
5. Maintain a healthy body weight: It helps to protect the joints and, in combination with a healthy diet, to reduce the uric acid concentration. However, you should radical fasting heals distance yourself This is because so-called ketone bodies are formed, which inhibit uric acid excretion. In addition, due to the rapid reduction in body mass, more purines are broken down and the uric acid concentration rises.
6. Dietary supplements after medical consultation: A large-scale study suggests that the daily intake of 500 to 1,500 mg of vitamin C effective protection against gout. Researchers suspect that it inhibits inflammatory processes and lowers uric acid concentration. However, it is important to maintain a healthy lifestyle. You should also consult a doctor before taking a high dose of dietary supplements.
A permanently elevated uric acid level has been shown to cause the wristsbut also the vessels and Internal organs. One is particularly painful gout attack, in which the uric acid crystals are broken down by a strong inflammatory reaction.
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To keep the uric acid so low that it can be completely excreted with the urine, you must go to a vegetarian, low-fat and low-fructose diet respect, think highly. The so-called DASH dietwhich aims for a long-term dietary change. In addition, the high-dose intake of Vitamins C to effectively reduce uric acid after medical consultation.
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