Estimates of whale mutation rates contribute to understanding evolutionary processes
Science
31 Aug 2023
Vol 381, Issue 6661
pp. 942–943
Abstract
Evolution happens when the code of life, DNA, is changed by the process of mutation. Mutations include deletions and insertions, rearrangements, and transpositions (moving DNA). However, it is the rate of point mutations, which affect a single site in the chain of nucleotides that make up DNA, that is most often considered. Knowing the rate and pattern of mutation is essential to understanding the process of evolution. This knowledge increases understanding of natural selection and has applications such as tracking demography and dating phylogenies, but calculating the mutation rate is not straightforward. On page 990 of this issue, Suárez-Menéndez et al. (1) use parent-offspring trios and genome sequences to estimate rates of point-mutational change from one generation to the next in four species of baleen whales in the North Atlantic: humpback (Megaptera novaeangliae), blue (Balaenoptera musculus), fin (Balaenoptera physalus), and bowhead (Balaena mysticetus).
Get full access to this article
View all available purchase options and get full access to this article.
References and Notes
1
M. Suárez-Menéndez et al., Science 381990 (2023).
2
W. Wei et al., Nat. Common. 134752 (2022).
3
LA Bergeron et al., Nature 615285 (2023).
4
D. Tejada-Martinez et al., Proc. R. Soc. Lond. Ser. B 28820202592 (2021).
5
SYW Ho et al., Syst. Biol. 60366 (2011).
6
D. Starling, Molecular and Genome Evolution (Sinauer, 2016).
7
S. Hoban et al., Biol. Conserv. 248108654 (2020).
8
AL Cypriano-Souza, TF da Silva, MH Engel, SL Bonatto, Genet. Mol. Biol. 41253 (2018).
9
S. Y. W. Ho, B. Shapiro, Mol. Ecol. Resour. 11423 (2011).
10
K. V. Parag, O. G. Pybus, C.-H. Wu, Syst. Biol. 71121 (2021).
11
P. Johri et al., PLOS Biol. 20e3001669 (2022).
12
S. Möller, L. du Plessis, T. Stadler, Proc. Natl. Acad. Sci. U.S.A. 1154200 (2018).
13
M de Bruyn, AR Hoelzel, GR Carvalho, M Hofreiter, Trends Ecol. Evol. 26405 (2011).
14
M. Lynch et al., Nat. Rev. Genet. 17704 (2016).
15
M. Lynch, Genome Biol. Evol. 31107 (2011).
Information & Authors
Information
Published In
Science
Volume 381 | Issue 6661
1 September 2023
Copyright
Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
Article versions
Submission history
Published in print: 1 September 2023
Permissions
Request permissions for this article.
Authors
Affiliations
Department of Biosciences, Durham University, Durham, UK.
Michael Lynch
Biodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ, USA.
Notes
Metrics & Citations
Metrics
Article Usage
Altmetrics
Citations
Cite as
- A. Rus Hoelzel
- Michael Lynch
,
The raw material of evolution.Science381,942-943(2023).DOI:10.1126/science.adk0121
Export citation
Select the format you want to export the citation of this publication.
View Options
Check Access
Media
Figures
Multimedia
Tables