The raw material of evolution | Science

The raw material of evolution | Science

Estimates of whale mutation rates contribute to understanding evolutionary processes

Science

31 Aug 2023

Vol 381, Issue 6661

pp. 942943

Abstract

Evolution happens when the code of life, DNA, is changed by the process of mutation. Mutations include deletions and insertions, rearrangements, and transpositions (moving DNA). However, it is the rate of point mutations, which affect a single site in the chain of nucleotides that make up DNA, that is most often considered. Knowing the rate and pattern of mutation is essential to understanding the process of evolution. This knowledge increases understanding of natural selection and has applications such as tracking demography and dating phylogenies, but calculating the mutation rate is not straightforward. On page 990 of this issue, Suárez-Menéndez et al. (1) use parent-offspring trios and genome sequences to estimate rates of point-mutational change from one generation to the next in four species of baleen whales in the North Atlantic: humpback (Megaptera novaeangliae), blue (Balaenoptera musculus), fin (Balaenoptera physalus), and bowhead (Balaena mysticetus).

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References and Notes

1

M. Suárez-Menéndez et al., Science 381990 (2023).

2

W. Wei et al., Nat. Common. 134752 (2022).

3

LA Bergeron et al., Nature 615285 (2023).

4

D. Tejada-Martinez et al., Proc. R. Soc. Lond. Ser. B 28820202592 (2021).

5

SYW Ho et al., Syst. Biol. 60366 (2011).

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D. Starling, Molecular and Genome Evolution (Sinauer, 2016).

7

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AL Cypriano-Souza, TF da Silva, MH Engel, SL Bonatto, Genet. Mol. Biol. 41253 (2018).

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S. Y. W. Ho, B. Shapiro, Mol. Ecol. Resour. 11423 (2011).

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K. V. Parag, O. G. Pybus, C.-H. Wu, Syst. Biol. 71121 (2021).

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P. Johri et al., PLOS Biol. 20e3001669 (2022).

12

S. Möller, L. du Plessis, T. Stadler, Proc. Natl. Acad. Sci. U.S.A. 1154200 (2018).

13

M de Bruyn, AR Hoelzel, GR Carvalho, M Hofreiter, Trends Ecol. Evol. 26405 (2011).

14

M. Lynch et al., Nat. Rev. Genet. 17704 (2016).

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M. Lynch, Genome Biol. Evol. 31107 (2011).

Information & Authors

Information

Published In

Science

Volume 381 | Issue 6661
1 September 2023

Copyright

Copyright © 2023 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Published in print: 1 September 2023

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Authors

Affiliations

Department of Biosciences, Durham University, Durham, UK.

Michael Lynch

Biodesign Center for Mechanisms of Evolution, Arizona State University, Tempe, AZ, USA.

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  • A. Rus Hoelzel
  • Michael Lynch

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The raw material of evolution.Science381,942-943(2023).DOI:10.1126/science.adk0121

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