Coronavirus – HAS proposes to generalize the serological test before vaccination, for SARS-cov-2, since May 31, the French vaccination campaign has entered a new phase; from now on, people over 18 years old, without conditions, will be able to be vaccinated.

In addition to the fact that it completes the first stage of the vaccination campaign in France, the day of May 31 was also marked by another major event, which can change the situation of the pandemic in France, and which we detail below. after.

Invited to the microphone of Radio Monte-Carlo this past Monday, Dominique Le Guludec announces that the HAS of which she is the president is currently looking into the possibility of generalizing the serological test before vaccination.

The adoption of this new protocol would make it possible to avoid booster doses for people with pre-existing antibodies against the SARS-CoV-2 virus, the ultimate goal being to vaccinate as many people as possible, in a minimum of time, in order to ” prevent the pandemic from spreading.

Generalize the serological test before vaccination.

Concretely, what will this imply; is it really safe to inject only one dose of vaccine to people who already have an immune response against Covid-19; what do the authorities think of this new protocol, in particular the ministry of health?

We will also talk about the importance of vaccinating the youngest to put an end to this global pandemic, especially since the EMA has just authorized the vaccination of 12-15 year olds, and as a simple reminder, people who have already undergone the disease, are currently only entitled to one dose.

A serological test – what is it?

A Covid-19 serological test or Covid-19 antibody test is a test used to detect antibodies in the blood against the COVID-19 virus developed by the body in contact with the SARS-Cov-2 virus, as is the case, for people who have already developed the disease.

Antibody tests differ from swab tests, which test to see if you currently have the virus, it is also important to note that a serological test does not tell if a person is immune to COVID-19 in the virus. insofar as the presence of antibodies in the body does not prevent further contamination.

A serological test at the time of the first dose

Having antibodies to the COVID-19 virus in your body does not completely protect you from the disease, however, new evidence suggests that it may ultimately have some benefits.

For quite some time now, many researchers around the world have been speculating that those who already have antibodies to the COVID-19 virus will only need a single dose of the vaccine to be fully immunized against the virus. .

Today, several serious studies confirm the veracity of this hypothesis; this is the reason why in France, the High Authority of Health (HAS) plans to standardize in the coming weeks the serological tests before the first dose of vaccine.

This would make it possible to know whether the person to be vaccinated needs one or two doses, this would clarify the situation, while increasing the number of people vaccinated, simultaneously responding to the shortage of the proposed doses.

This news was announced on May 31st. Asked about RMC, Dominique Le Guludec, president of the HAS explains that they are currently working on the development of an official document which will frame the “trivialization” of serological tests at the time of the injection of the first dose. vaccine against Covid-19.

At the microphone of RMC, she also argued that very few recontaminations have been detected in the millions of cases recorded worldwide, this means that a Covid-19 infection really requires a reliable immune response.

And also that for people with this immune response, a single dose of vaccine is enough, and this is what is currently practiced for people who have already suffered from the virus and the pandemic, who are only entitled to one vaccine. single dose.

Let’s talk about the new vaccine before the serological tests

Not many people know them, but as a general rule to produce a vaccine, it takes between 8 and 10 years, but with the will to stop this global pandemic, the new vaccine, will have taken less than a year, to be produced, distributed and broadcast, it’s a real revolution.

The inventors are a married couple of two German immigrants (origin Turkey), they used a technique never used for humans (practiced for animals), but not for human beings, called by experts “genetic engineering”.

This consists of injecting a decoy, which is called mRNA (messenger) instead of a deactivated virus, or an attenuated virus, and the body will train to fight against to elicit an immune response, by teaching it to recognize the target virus (and ultimately destroy it).

Great medical and technological breakthrough, for the whole world.

Experts consider this to be a very great medical breakthrough for science and for humanity, a promising and innovative promise, and the two most advanced laboratories on the vaccine project are: BioNTech (German), and American Moderna, directed by a French.

According to specialized journals, 1 billion 300 thousand doses, are planned in production for the year 2021 alone, only one downside, its conservation, under current conditions, it must be stored in super freezers, at minus 70 or minus 80 degrees.

Scientists calculate that the success rate is around 94%, this is very promising, when compared to other vaccines, such as the annual flu vaccine only advertised for 40 to 50% success. .

What should be remembered is that new vaccine technologies are disrupting the practices known until now, those concerning DNA or mRNA molecules (message), are turning out to be a big step forward for science. , and let us hope for a better future.

Generalization of serological tests before vaccination – a protocol soon to be approved

This HAS proposal is still under development, it is awaiting approval, in particular by the Ministry of Health; and this should take longer, because Dominique Le Guludec has already mentioned the fact that this HAS proposal will be clarified in the coming days.

For his part, the Minister of Health Olivier Véran has also already mentioned the importance of this new protocol, he has also already approached the health authorities to try to find out whether people who already have antibodies against Covid-19 really do need more than a single dose.

For the Minister of Health, the adoption of this new protocol can only be a matter of “very good news”, because it will make it possible to accelerate the vaccination campaign and also to reduce its cost, which increases every year. day, and becomes considerable.

Other specialists even go so far as to argue that it would drastically reduce the chances of emergence of vaccine-resistant mutants, such as the already problematic variants of the United Kingdom, South Africa and Brazil.

Vaccination of the youngest – the new priority of the authorities

According to specialists, those under 18 have a low risk of contracting Covid-19, and when this is the case, they most often develop mild forms of the disease, so they should be vaccinated, to avoid spread the pandemic, but it is not a priority.

And given that for the time being, there are still many elderly people who have not yet all been vaccinated (21% of over 70s, 26% of over 60s and 34% of over 50s), the authorities prefer make the vaccination of the youngest their new priority.

This is certainly an excellent strategy to limit the spread of the coronavirus to the most vulnerable, a strategy that can finally be deployed, because vaccination with the Pfizer vaccine for 12-18 year olds has just been authorized within the ‘EU, which was not the case before May 29.

And for information also, know that the Pfizer vaccine already has a marketing authorization for people over 16 years old. At the moment, nothing is therefore preventing all European countries from vaccinating the youngest, at least for certain categories.

As far as France is concerned, with the vaccination of people over 18 years old which has already started, the vaccination of adolescents is now the next and the last step which will really help to put an end to this global pandemic.

And since this is a new priority, the vaccination of adolescents aged 12 to 18 will be launched quickly, while the authorities initially planned to do so in early September 2021, however, no date has yet been set. disclosed.

Author Antonio Rodriguez, Director of Clever Technologies.

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