Over 200 Symptoms Associated With Long Covid

Covid infection generates a myriad of long-term symptoms, some of which persist well beyond six months. But are they really due to the Covid?

The largest study of people with long-term Covid (symptoms persisting for more than four weeks after initial infection) reveals an extremely complex pathology, with a myriad from symptoms as diverse as memory loss, tremors, tinnitus, itching, disorders of menstrual cycle, palpitations or blurred vision and diarrhea. A total of 203 different symptoms have been reported.

The study, published in the journal ClinicalMedicine from The Lancet, interviewed 3,762 people with confirmed or suspected long-term Covid in 56 countries. The 2,454 patients still showing symptoms beyond six months (65% of the sample) had an average of 13.8 symptoms and just 233 patients (6%) were fully recovered.

« Many post-Covid services have focused on respiratory rehabilitation. It is true that many patients suffer from shortness of breath, but they also have many other types of symptoms that doctors need to provide a more comprehensive approach to. Insists Athena Akrami, a neuroscientist at theUniversity College from London and lead author of the study.

No hasty conclusions

However, beware of hasty conclusions: just like the so-called side effects falsely attributed to anti-Covid vaccines, many symptoms could actually have other causes than the Covid. In addition, as the study was conducted using an online questionnaire, it could suffer from selection bias (the most affected people being more prompt to respond).

Covid long: 6 in 10 hospital patients still suffer from at least one symptom after 6 months

Article by Insu published on 05/17/2021

Faced with this problem of the “long Covid”, scientists are still wondering about this new virus SARS-CoV-2 and the long-term consequences of the disease it causes. In a study, the investigators of the French Covid cohort, promoted by Inserm, show that 60% of hospitalized patients present at least one symptom after their infection 6 months.

Is it possible to show symptoms of Covid-19 several months after being infected with Sars-CoV-2? How long can symptoms of Covid-19 persist after hospitalization for this infection? The subject of the “long Covid” still questions the scientific and medical community. It is at the heart of several research works, in particular those carried out by the investigators of the cohort French Covid, promoted by Inserm which show in a new study published in the journal CMI, that a significant proportion of patients who have been hospitalized and monitored as part of French Covid still present symptoms 3 and 6 months after infection.

Launched at the end of January 2020, French Covid is a French cohort study promoted by Inserm, bringing together these researchers from Inserm, AP-HP and the University of Paris. It is based on the monitoring of a large group of patients who have developed a clinical form of the disease which required hospitalization, either in a medical department or in intensive care. As of March 17, 2021, 4,310 patients had been included in this cohort, the largest French cohort to date of patients hospitalized for SARS-CoV-2 infection.

These studies suggest that 60% of patients are still affected by at least one symptom six months after infection and a quarter of them by three or more symptoms.

For each participant, clinical, virological, immunological, genetics, serological and transcriptomics are collected in order to better characterize the disease. The objective is to accumulate knowledge on Covid-19, in particular on the most serious forms in order to improve care in cases where hospitalization is required. It is also about better understanding the future of patients in the short and long term by focusing on the possible persistence of symptoms in the months following the diagnosis.

What Are the Persistent Symptoms of Long Covid?

In their new study, the team describes the frequency and nature of persistent symptoms in 1,137 patients from French Covid, assessed during follow-up visits at 3 and 6 months after hospitalization for Covid-19. These studies suggest that 60% of patients are still affected by at least one symptom six months after infection and a quarter of them by three or more symptoms.

In addition, 2% of patients had to be hospitalized again. A strong feeling of fatigue, breathing difficulties and pains muscle and joint were among the most frequently reported persistent clinical manifestations during these follow-up visits. A correlation between initial severity disease and long-term persistence of symptoms also appear to be emerging.

Women seem more at risk of suffering from symptoms that persist over time

Indeed, the persistence of at least 3 symptoms six months after infection is more frequent in people whose Covid-19 disease required a stay in intensive care compared to those who were hospitalized in a medical department, and in the most symptomatic patients on the day of admission to hospital. Researchers also observe gender differences: if men are more at risk severe forms, women seem to be more at risk of suffering from persistent symptoms in the duration.

The difficult return to active life

The study finally underlines that these forms of ” long covid Sometimes have wider consequences, both economically and socially. Thus, among the patients who report symptoms at 6 months and who were working when they were infected, a third did not return to work. To better understand the consequences of the virus on the body and the long-term impact of the disease, and above all to better manage patients, continuing this monitoring beyond 6 months in an even larger population could present a problem. certain interest.

« The mechanisms behind the persistence of symptoms as the body sheds the virus are still unclear. We will continue to monitor patients included in French Covid up to 18 months after infection, by also offering tests evaluating the neuro-cognitive functions», Underlines Jade Ghosn, cohort coordinator, PU-PH University of Paris and professor in the infectious and tropical diseases department of Bichat Claude-Bernard AP-HP Hospital.

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Influenza vaccination apparently prevents severe Covid-19 courses

Even if the corona vaccination is currently on everyone’s lips: The spades against flu can also affect a Covid 19 disease. He could avert serious illnesses.

The Standing Vaccination Commission recommends the flu vaccination every year to people over 60 years of age, the chronically ill or, for example, health and nursing staff. These groups of people were also identified at the start of the vaccination campaign against the Coronavirus prioritized.

70 million data analyzed

Now it shows: The antiInfluenza-Piks could also have an impact on the course of the disease after a corona infection. Researchers at the University of Miami analyzed the anonymized health data of over 70 million patients and filtered out 37,000 people from the USA, Great Britain, Germany, Israel, Italy and Singapore. Everyone was on Covid-19 ill.

The filters were based on characteristics such as similar age, similar social status, gender and previous illnesses. With pre-existing conditions it is known that, for example Diabetes, Obesity or the lung disease COPD influence the severity of the course of the disease and these patients have a higher risk of hospitalization (admission to hospital).

Risk of emergency admission reduced by 58 percent

A distinction was made into two groups: One had received a flu vaccination at least two weeks to six months before the diagnosis of corona infection. The other one doesn’t.

The results were clear: Those who had been vaccinated against the flu had a lower risk of serious disease progression in the first 120 days after the corona infection. The risk of being taken to the emergency room was 58 percent lower than that of the unvaccinated. The likelihood of ending up in the intensive care unit was reduced by 20 percent.

And other complications of Covid 19 disease were also significantly more common in unvaccinated people. The risk of heart attacks and strokes related to corona also decreased by 58 percent among those vaccinated, that for one Blood poisoning by 45 percent. The risk of deep vein thrombosis was 45 percent higher in unvaccinated people.

Other studies with similar results

The connection between a Flu shot and an effect on the course of Covid 19 disease has already been proven in other studies. An analysis by the University of Michigan in February came to the conclusion that a flu vaccination can also protect against corona infection.

Here, data from more than 27,000 patients were filtered again. They had been tested for the corona virus between March and July 2020. 13,000 of them had influenza in the previous yearvaccination receive. 14,000 were unvaccinated. In the vaccinated group, four percent were infected with the coronavirus, in the unvaccinated group it was five percent.

Similar results were also obtained Dutch researchers and scientists from Heinrich Heine University Düsseldorf. The Michigan study also demonstrated a positive effect of the flu vaccination on the severity of the Covid disease course.

The exact connection has not yet been explored. The British newspaper “The Guardian” quotes infection researcher Peter Openshaw as saying: “One explanation for this could be that the flu vaccination stimulates the immune system as a whole and can bring about these positive effects.”

Hope for the poor countries?

And there is another aspect that the findings could be important. The flu protection could hardly be in countries in which so far Corona vaccine has arrived, help to reduce the severity of the disease.

“Only a small fraction of the world has been fully vaccinated against Covid-19 so far,” explains Dr. Devinder Singh, lead author of the Miami study. His team was able to observe a connection between the flu vaccine and lower morbidity in Covid 19 patients.

“This finding is particularly significant because the pandemic is a drain on resources in many parts of the world. Therefore, our research – if validated by prospective randomized clinical trials – has the potential to reduce the global burden of disease.”

No substitute for corona vaccination

However, his colleague Susan Taghioff adds: “Even so, the flu vaccine is not a substitute for the Covid-19 vaccine and we are committed to ensuring that everyone receives their Covid-19 vaccine when possible.”

Important NOTE: The information is in no way a substitute for professional advice or treatment by trained and recognized doctors. The contents of t-online cannot and must not be used to independently make diagnoses or start treatments.

.

Influenza vaccination apparently prevents severe Covid-19 courses

Even if the corona vaccination is currently on everyone’s lips: The spades against flu can also affect a Covid 19 disease. He could avert serious illnesses.

The Standing Vaccination Commission recommends the flu vaccination every year to people over 60 years of age, the chronically ill or, for example, health and nursing staff. These groups of people were also identified at the start of the vaccination campaign against the Coronavirus prioritized.

70 million data analyzed

Now it shows: The antiInfluenza-Piks could also have an impact on the course of the disease after a corona infection. Researchers at the University of Miami analyzed the anonymized health data of over 70 million patients and filtered out 37,000 people from the USA, Great Britain, Germany, Israel, Italy and Singapore. Everyone was on Covid-19 ill.

The filters were based on characteristics such as similar age, similar social status, gender and previous illnesses. In the case of previous illnesses, it is known that, for example Diabetes, Obesity or the lung disease COPD influence the severity of the course of the disease and these patients have a higher risk of hospitalization (admission to hospital).

Risk of emergency admission reduced by 58 percent

A distinction was made into two groups: One had received a flu vaccination at least two weeks to six months before the diagnosis of corona infection. The other one doesn’t.

The results were clear: Those who had been vaccinated against the flu had a lower risk of serious disease progression in the first 120 days after the corona infection. The risk of being taken to the emergency room was 58 percent lower than that of the unvaccinated. The likelihood of ending up in the intensive care unit was reduced by 20 percent.

And other complications of Covid 19 disease were also significantly more common in unvaccinated people. The risk of heart attacks and strokes related to corona also decreased by 58 percent among those vaccinated, that for one Blood poisoning by 45 percent. The risk of deep vein thrombosis was 45 percent higher in unvaccinated people.

Other studies with similar results

The connection between a Flu shot and an effect on the course of Covid-19 disease has already been proven in other studies. An analysis by the University of Michigan in February came to the conclusion that a flu vaccination can also protect against corona infection.

Here, data from more than 27,000 patients were filtered again. They had been tested for the corona virus between March and July 2020. 13,000 of them had influenza in the previous yearvaccination receive. 14,000 were unvaccinated. In the vaccinated group, four percent were infected with the coronavirus, in the unvaccinated group it was five percent.

Similar results were also obtained Dutch researchers and scientists from Heinrich Heine University Düsseldorf. The Michigan study also demonstrated a positive effect of the flu vaccination on the severity of the Covid disease course.

The exact connection has not yet been explored. The British newspaper “The Guardian” quotes infection researcher Peter Openshaw as saying: “One explanation for this could be that the flu vaccination stimulates the immune system as a whole and can bring about these positive effects.”

Hope for the poor countries?

And there is another aspect that the findings could be important. The flu protection could hardly be in countries in which so far Corona vaccine has arrived, help reduce the severity of the disease.

“Only a small fraction of the world has been fully vaccinated against Covid-19 so far,” explains Dr. Devinder Singh, lead author of the Miami study. His team was able to observe a connection between the flu vaccine and lower morbidity in Covid 19 patients.

“This finding is particularly significant because the pandemic is a drain on resources in many parts of the world. Therefore, our research – if validated by prospective randomized clinical trials – has the potential to reduce the global burden of disease.”

No substitute for corona vaccination

However, his colleague Susan Taghioff adds: “Even so, the flu vaccine is not a substitute for the Covid-19 vaccine and we are committed to ensuring that everyone receives their Covid-19 vaccine when possible.”

Important NOTE: The information is in no way a substitute for professional advice or treatment by trained and recognized doctors. The contents of t-online cannot and must not be used to independently make diagnoses or start treatments.

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Doctors warn of sudden corona symptoms: Rare, but underestimated

Shortness of breath, fatigue, muscle pain: the list of possible long-term consequences with Covid-19 is long. New studies show that problems with the ears can apparently also be a permanent symptom.

An infection with the Coronavirus can lead to consequential damage even with mild courses. In most cases, those affected complain of long-term neurological disorders such as a loss of the sense of smell or exhaustion and shortness of breath. Serious Covid-19 diseases can lead to dangerous lung or brain damage. But other parts of the body can also be immensely damaged, such as the middle ear.

Long-term complication: sudden hearing loss due to corona?

British ear, nose and throat doctors described the first case of sudden and permanent hearing loss as a result of Covid-19 as early as 2020 according to the “Pharmazeutische Zeitung”. A 45 year old man with Asthma had been treated in hospital for a corona infection and suffered tinnitus in the left ear as a result of the disease, followed by sudden complete hearing loss in the same ear.

What is tinnitus? With tinnitus – also known as ringing in the ears – those affected perceive humming, booming or whistling noises in their ears that do not want to go away. Depending on the severity, this can be a heavy burden.

The doctors did not find any inflammation in the ear or other possible causes, such as rheumatoid arthritis, influenza or HIV infection, that could lead to sudden hearing loss. They therefore suspected a causal relationship between the SARS-CoV-2-Infection and hearing loss. This is supported by the fact that coronaviruses could attack the epithelial cells in the middle ear.

Study reveals how common hearing damage and tinnitus occur with Covid-19

Case reports of corona patients who complain of impaired hearing and tinnitus are now increasing. “In the past few months I have received countless emails from people who have reported changes in their hearing or a Tinnitus reported after Covid-19, “said Kevin Munro, an audiologist at the University of Manchester.” There is therefore an urgent need to study the long-term effects of Covid-19 on the auditory system. “

Together with his colleague Ibrahim Almufarrij, Munro carried out a meta-study. They evaluated 56 examinations in which an increased incidence of hearing impairment in the course of a corona infection was described.

The result of the study published in the “International Journal of Audiology”: On average, 14.8 percent of Covid 19 patients reported that their tinnitus got worse or that such a ringing in the ear reappeared after they were discharged from the hospital. 7.6 percent suffered prolonged hearing loss. This usually started abruptly and affected both ears, but there have also been a few cases in which hearing loss gradually developed or only affected one ear. The hearing impairment occurred in both mild and severe patients – the majority of them were male.

According to the study authors, these results suggest that Covid-19 can also affect the ears and hearing aid. However, the causes have not yet been conclusively researched. There could be several mechanisms by which the infection directly or indirectly attacks the hearing aid, they explain. The virus itself, circulatory disorders or the immune system come into question.

Connection between tinnitus and Covid-19 already proven

An international team of researchers from England, Belgium, the USA, the Netherlands, Sweden and India had already dealt with the question of how a corona infection affects people with tinnitus in 2020. For this purpose, data from 3,103 tinnitus patients from 48 countries were evaluated.

The result: 40 percent of those who suffered from Covid 19 symptoms said that their tinnitus had also worsened. Seven people also stated that they suspect that the tinnitus was only triggered by Corona. The researchers concluded that there was a link between the infection and the tinnitus. A study by German researchers at the Tinnitus Center at the University of Regensburg confirmed this. Accordingly, an increased stress level – triggered by the Corona-pandemic – act as a tinnitus trigger.

Pay more attention to hearing problems with Corona

Reports of hearing loss as a result of Covid-19 are so far rather rare, but doctors advise Covid-19 patients to be careful and have themselves examined at the first signs of hearing loss. This is especially important because rapid therapy with so-called corticosteroids can reverse the hearing loss.

Important NOTE: The information is in no way a substitute for professional advice or treatment by trained and recognized doctors. The contents of t-online cannot and must not be used to independently make diagnoses or start treatments.

.

Doctors warn of sudden corona symptoms: Rare, but underestimated

Shortness of breath, fatigue, muscle pain: the list of possible long-term consequences with Covid-19 is long. New studies show that problems with the ears can apparently also be a permanent symptom.

An infection with the Coronavirus can lead to consequential damage even with mild courses. In most cases, those affected complain of long-term neurological disorders such as a loss of the sense of smell or exhaustion and shortness of breath. Serious Covid-19 diseases can lead to dangerous lung or brain damage. But other parts of the body can also be immensely damaged, such as the middle ear.

Long-term complication: sudden hearing loss due to corona?

British ear, nose and throat doctors described the first case of sudden and permanent hearing loss as a result of Covid-19 as early as 2020 according to the “Pharmazeutische Zeitung”. A 45 year old man with Asthma had been treated in hospital for a corona infection and suffered tinnitus in the left ear as a result of the disease, followed by sudden complete hearing loss in the same ear.

What is tinnitus? With tinnitus – also known as ringing in the ears – those affected perceive humming, booming or whistling noises in their ears that do not want to go away. Depending on the severity, this can be a heavy burden.

The doctors did not find any inflammation in the ear or other possible causes, such as rheumatoid arthritis, influenza or HIV infection, that could lead to sudden hearing loss. They therefore suspected a causal relationship between the SARS-CoV-2-Infection and hearing loss. This is supported by the fact that coronaviruses could attack the epithelial cells in the middle ear.

Study reveals how common hearing damage and tinnitus occur with Covid-19

Case reports of corona patients who complain of impaired hearing and tinnitus are now increasing. “In the past few months I have received countless emails from people who have reported changes in their hearing or a Tinnitus reported after Covid-19, “said Kevin Munro, an audiologist at the University of Manchester.” There is therefore an urgent need to study the long-term effects of Covid-19 on the auditory system. “

Together with his colleague Ibrahim Almufarrij, Munro carried out a meta-study. They evaluated 56 examinations in which an increased incidence of hearing impairment in the course of a corona infection was described.

The result of the study published in the “International Journal of Audiology”: On average, 14.8 percent of Covid-19 patients reported that their tinnitus got worse or that such a ringing in the ear reappeared after they were discharged from the hospital. 7.6 percent suffered prolonged hearing loss. This usually started abruptly and affected both ears, but there have also been a few cases in which hearing loss gradually developed or only affected one ear. The hearing impairment occurred in both mild and severe patients – the majority of them were male.

According to the study authors, these results suggest that Covid-19 can also affect the ears and hearing aid. However, the causes have not yet been conclusively researched. There could be several mechanisms by which the infection directly or indirectly attacks the hearing aid, they explain. The virus itself, circulatory disorders or the immune system come into question.

Connection between tinnitus and Covid-19 already proven

An international team of researchers from England, Belgium, the USA, the Netherlands, Sweden and India had already dealt with the question of how a corona infection affects people with tinnitus in 2020. For this purpose, data from 3,103 tinnitus patients from 48 countries were evaluated.

The result: 40 percent of those who suffered from Covid 19 symptoms said that their tinnitus had also worsened. Seven people also stated that they suspect that the tinnitus was only triggered by Corona. The researchers concluded that there was a link between the infection and the tinnitus. A study by German researchers from the Tinnitus Center at the University of Regensburg was able to confirm this. Accordingly, an increased stress level – triggered by the Corona-pandemic – act as a tinnitus trigger.

Pay more attention to hearing problems with Corona

Reports of hearing loss as a result of Covid-19 are so far rather rare, but doctors advise Covid-19 patients to be careful and have themselves examined at the first signs of hearing loss. This is especially important because rapid therapy with so-called corticosteroids can reverse the hearing loss.

Important NOTE: The information is in no way a substitute for professional advice or treatment by trained and recognized doctors. The contents of t-online cannot and must not be used to independently make diagnoses or start treatments.

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Guillain-Barré syndrome is triggered by anti-Covid vaccines

The Guillain-Barré syndrome is the new adverse effect produced by some of the vaccines antiCovid, some of them are AstraZeneca-Oxford, Pfizer-BioNTech Y Johnson & Johnson. Although it has affected very few people, its manifestation is worrying, since it encourages the Facial paralysis, and if it gets complicated, it could trigger areflexic quadriplegia and the need for respiratory assistance.

Interest in this neurological disorder arose after the Food and Drug Administration (FDA), from the United States, will notify through Federal System for Notification of Adverse Events to Vaccines (VAERS, for its acronym in English), 95 provoked cases of this syndrome, which required hospitalization.

However, Guillain-Barré syndrome (GBS) had already been detected in seven vaccinated people, with the AstraZeneca vial, in India. This manifestation occurred in the first four weeks, after having received the first dose.

Read also: US alert for cases of Guillain-Barré syndrome linked to Johnson & Johnson vaccine

From there, different research groups have devoted themselves to delving into its appearance, because although this condition is very unusual, it is potentially serious and can cause death.

That is why experts suggested that it is a variant of the disease. This is consistent with the GBS description published by “ScienceDirect”, in which they state that it encompasses a number of different “recognizable variables.”

One of the efforts around this phenomenon was published in the “Wiley Online Library”. The scientists studied four of the seven cases, in which the affected patients were women who ranged from 43 to 68 years, (only one of the seven affected was male) in the Kerala Medical Center, on the costa Malabar india.

Read also: Myocarditis, the new adverse effect of the Pfizer and Moderna anti-Covid vaccines

Among the symptoms reported by the mourners, weakness in the limbs predominated, facial numbness and lingual, difficulty passing food -dysphagia-, as well as back pain.

As of the date the results were released, on June 10, 2021, the researchers said that of the seven GBS patients, six had not recovered and one had been discharged. All of them required mechanic ventilation to control the effects of the syndrome.

The experts concluded that this disease occurs very infrequently, registering 17 cases per one million inhabitants per year. But they urged the health authorities to pay attention and plan a way to address the events that may occur during the anti-Covid vaccination days, as their effects are serious.

“Overall, our experience should prompt all clinicians to be vigilant in recognizing GBS in vaccinated patients. While the risk per patient may be relatively low, our observations suggest that this clinically distinct GBS variant is more severe than usual and may require mechanical ventilation, “says the document.

Read also: Alcohol and Covid Vaccination: Expert Unravels What Happens If We Combine Them

What else is known about Guillain-Barré syndrome?

This disease is part of the conditions that attack the immune system. The GBS specifically attacks the nerve cells.

The neurons, as they are better known, establish connections with muscle cells Y glandulares for the proper functioning of the nervous system.

When a person has GBS they will experience symptoms for about two weeks. However, the disease can cause irreversible damage.

The causes have been associated as a secondary effect of a primary disease, this can be a Respiratory infection, such as seasonal flu, or gastrointestinal like salmonella. They usually present 7 to 15 days after the onset of the disease.

Read also: Covid-19: Lambda variant could be as transmissible as Delta and is already in 29 countries

According to the Centers for Disease Control and Prevention (CDC), this disease is more common in men over 50 years of age.

To date, scientific evidence has not proven about the genetic or social factors that cause a small number of patients to suffer from it.

The recovery of GBS can be favorable, if it is treated on time and with constant medical follow-up, that is why experts recommend that treatment begin immediately after being diagnosed.

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First cases of the Delta variant in Portugal associated with travel to India and Nepal

“We believe, according to the epidemiological data we have to date, that the start was associated with a high number of introductions in the Lisbon region, particularly in the Lisbon area”, underlines the microbiologist of the National Health Institute Doctor Ricardo Jorge (INSA).

João Paulo Gomes also considers that the introduction of the Delta variant in Portugal has “little association with the United Kingdom”.

“We have many cases, most of the first recorded cases were associated with travel to India and Nepal, and we know that we have a very relevant Indian community in the center of Lisbon”, adds the microbiologist.

These trips will have been at the origin of “innumerable transmission chains”.

In the Algarve and Lisbon and Vale do Tejo regions, this variant already represents all (100 percent) of the cases of infection.

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According to the study, eradication or elimination is hardly possible

A new study provides information on the eradication and elimination of Covid-19. It is very unlikely that the virus will go away completely.

the essentials in brief

  • The eradication of SARS-CoV-2 is becoming increasingly unlikely.
  • Local eliminations are still possible for a few states.
  • This would require protection against current and future virus variants.

According to a study, Covid-19 eradication or elimination is probably not realistic. However, local elimination does. However, it is unlikely that the virus will completely disappear.

“Elimination could well represent a more realistic short-term goal for SARS-CoV-2.” That is what it says in a study that was published on Friday in the Journal of the American Medical Association JAMA.

In Israel, for example, elimination is within reach. New Zealand, Vietnam and Brunei may also be on the verge of this. The United Kingdom, the United States and China, on the other hand, are currently more in a state of cohabitation.

This means that they try to cope with the virus there. In India, other parts of Southeast Asia and a large part of South America, however, the virus is currently still raging like a wildfire.

Sufficient herd immunity would be necessary for Covid-19 eradication or elimination

“Even as a thought experiment, extermination is too ambitious a goal”. That’s what the scientists working with Aaron Kaufman from Emory University think. They are a reminder that smallpox has been eradicated, although that was once considered unimaginable.

Compared to smallpox, there is an aggravating risk with Covid-19: zoonotic transmission by bats, farmed minks or animal reservoirs that have not yet been discovered. There was no such reservoir for smallpox.

In order to prevent zoonotic transmission, vaccination against SARS-CoV-2 and its variants would have to be continued. In order to achieve global extinction, “sufficient herd immunity would have to be achieved through vaccination and prior infection.

This immunity should be “highly effective and long-lasting, preventing secondary transmission and reinfection. And protect against all kinds of current and future virus variants ». These are extremely strict requirements.

Wildfire possible in some countries

According to the authors of the study, a viable alternative to extermination and elimination would be a civilized coexistence with SARS-CoV-2. In this scenario, the protection of the vaccine would go further. He would have to prevent the most severe manifestations of COVID-19 and break the chain of virus transmission.

The prerequisites would be the global availability of vaccines, the reduction of reluctance to vaccinate and the reduction in the number of variants. “When global immunity becomes commonplace, the symptoms of the disease can resemble those of a cold.”

The worst endgame scenario, wildfire, could occur where there are gaps in vaccine supply. And / or there is a great reluctance to vaccinate. Unchecked contagion by non-immunized people would allow the virus to develop continuously, which makes it even more difficult to contain.

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Corona quo vadis? SARS-CoV-2 in the future – three scenarios presented – healing practice

Possible development of the coronavirus SARS-CoV-2

As part of a current study, a research team examined how the coronavirus SARS-CoV-2 will develop in the coming years. Three scenarios are the most likely.

“There is a realistic expectation that global vaccination efforts will bring the SARS-CoV-2 coronavirus pandemic under control.” This is the assessment made by the research team headed by Amalio Telenti and Davide Corti. However, a complete eradication of the virus is unrealistic. How SARS-CoV-2 will likely encounter us in the future is described by the working group in three possible scenarios that are presented in the renowned specialist journal “Nature”.

How will SARS-CoV-2 establish itself in the future?

There is great uncertainty as to whether and in what way the coronavirus SARS-CoV-2 will establish itself in the human population worldwide in the future. Will COVID-19 become an endemic disease with seasonal epidemic peaks similar to influenza, or will COVID-19 one day become a harmless cold? The research team gives an outlook on the basis of relevant observations from previous epidemics and on the basis of the information available on the evolution of SARS-CoV-2.

Scenario 1: SARS-CoV-2 remains uncontrollable

In the most unsettling scenario that the working group describes, mankind fails to bring the virus under control. Constantly changing variants will ensure that the course will continue to be difficult and that there will be high numbers of infected people in the future, which means that there is still a high risk that new mutations will continuously prevail.

Scenario 2: COVID-19 becomes a seasonal disease

However, the researchers believe that it is more likely that COVID-19 will become a seasonal disease like the flu. More effective treatments, which are continuously developed, ensure that both the severity of the disease and the number of hospital stays as well as the number of deaths will decrease massively.

But the flu is also a serious infectious disease that causes several hundred thousand deaths per year, the research team points out. Another viral infection on this scale puts a significant strain on health systems.

Scenario 3: COVID-19 becomes a harmless cold

In many people who became infected with SARS-CoV-2, the disease was very mild or was not noticed at all. If a certain immunity has set in in the population, it is conceivable that the severity of the disease from COVID-19 will decrease over time and assimilate to the well-known coronaviruses, which tend to cause harmless colds. This is the most optimistic scenario the researchers describe.

Comparison with the Spanish flu

The team also draws a comparison with the Spanish flu, which was particularly severe in 1918 and 1919. According to the working group, offspring of the influenza pathogen H1N1 caused epidemics well into the 1950s. According to the researchers, the main requirement for a weakening of SARS-CoV-2 is widespread immunity in the population.

Why the virus could get out of control

One of the greatest dangers is that a variant develops that is able to overcome the immunity of those who have recovered and who have been vaccinated. Every region in which SARS-CoV-2 cannot be brought under control increases the risk that such a variant will develop. In addition, there is also the risk that SARS-CoV-2 will develop further in animal species and spread back over to humans.

Predicting such developments is only possible to a limited extent with the tools currently available. The scientists recommend increasing research efforts in this area.

Hopeful conclusion

Overall, the team comes to the conclusion that the evolution of SARS-CoV-2 may be restricted in view of the relatively limited number of mutations and variants. If this assumption is true, the virus may not get any worse than it is now. (vb)

Author and source information

This text complies with the requirements of specialist medical literature, medical guidelines and current studies and has been checked by medical professionals.

Author:

Diploma-Editor (FH) Volker Blasek

Swell:

  • Telenti, A., Arvin, A., Corey, L. et al. After the pandemic: perspectives on the future trajectory of COVID-19; in: Nature, 2021, nature.com
  • Deutsches Ärzteblatt: Three scenarios for a future with SARS-CoV-2 (published: July 9th, 2021), aerzteblatt.de

Important NOTE:
This article is for general guidance only and is not intended to be used for self-diagnosis or self-treatment. He can not substitute a visit at the doctor.

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Influenza vaccination prevents some serious Covid-19 consequences

In addition to a specific protective reaction against the respective pathogen, vaccinations also cause a general activation of the innate immune system. And people apparently benefit from this activation when they contract Covid-19. This effect has already been described for the measles, mumps, rubella and polio vaccinations and has now also been confirmed for the flu vaccination by US researcher Susan Taghioff from the University of Miami and her team.

Over 30,000 examined from America, Europe and Asia

Taghioff and colleagues used the TriNetX database, in which anonymized data is collected from over 70 million patients from numerous countries. In it, the researchers searched for Covid-19 patients and filtered them by age, gender, social status and the severe complications described by Covid-19, such as diabetes, obesity and COPD. They were able to put together two groups with a total of 37,377 people from the USA, the United Kingdom, Germany, Italy, Israel and Singapore.

The study group had been vaccinated against flu for at least two weeks and a maximum of six months before the Covid diagnosis, the control group was not. Clear result of the comparison: Those who had received the flu vaccination had a lower risk of suffering strokes and heart attacks, sepsis or deep vein thrombosis within 120 days of a positive test for Sars-CoV-2.

Influenza vaccination lowers hospital admissions by 58 percent

According to the analysis, those who had been vaccinated against influenza had up to 58 percent lower risk of ending up in the emergency room and had to be treated in an intensive care unit up to 20 percent less often. The risk of heart attacks and strokes associated with Covid-19 also decreased by 58 percent, that of sepsis by 45 percent and that of deep vein thrombosis by 40 percent.

The study was presented at the European Congress for Clinical Microbiology and Infectious Diseases. The results are to be published in a journal, but there is currently no written publication.

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