Covid infection generates a myriad of long-term symptoms, some of which persist well beyond six months. But are they really due to the Covid?
The largest study of people with long-term Covid (persisting for more than four weeks after initial infection) reveals , with a from as memory loss, tremors, tinnitus, , disorders of , palpitations or blurred vision and . A total of 203 different symptoms have been reported.
The study, published in the journalfrom The Lancet, interviewed 3,762 people with confirmed or suspected long-term Covid in 56 countries. The 2,454 patients still showing symptoms beyond six months (65% of the sample) had an average of 13.8 symptoms and just 233 patients (6%) were fully recovered.
« Many post-Covid services have focused on respiratory rehabilitation. It is true that many patients suffer from shortness of breath, but they also have many other types of symptoms that doctors need to provide a more comprehensive approach to. Insists Athena Akrami, a neuroscientist at theUniversity College from London and lead author of the study.
No hasty conclusions
However, beware of hasty conclusions: just like the, many symptoms could actually . In addition, as the study was conducted using an online questionnaire, it could suffer from selection bias (the most affected people being more prompt to respond).
Covid long: 6 in 10 hospital patients still suffer from at least one symptom after 6 months
Article by Insu published on 05/17/2021
Faced with this problem of the “long Covid”, scientists are still wondering about this newSARS-CoV-2 and the long-term consequences of the disease it causes. In a study, the investigators of the French Covid cohort, promoted by Inserm, show that 60% of hospitalized patients present at least one symptom after their infection 6 months.
Is it possible to show symptoms of Covid-19 several months after being infected with Sars-CoV-2? How long can symptoms of Covid-19 persist after hospitalization for this infection? The subject of the “long Covid” still questions the scientific and medical community. It is at the heart of several research works, in particular those carried out by the investigators of the cohort, promoted by Inserm which show in a new study published in the , that a significant proportion of patients who have been hospitalized and monitored as part of French Covid still present symptoms 3 and 6 months after infection.
Launched at the end of January 2020, French Covid is a French cohort study promoted by Inserm, bringing together these researchers from Inserm, AP-HP and the University of Paris. It is based on the monitoring of a large group of patients who have developed a clinical form of the disease which required hospitalization, either in a medical department or in intensive care. As of March 17, 2021, 4,310 patients had been included in this cohort, the largest French cohort to date of patients hospitalized for SARS-CoV-2 infection.
These studies suggest that 60% of patients are still affected by at least one symptom six months after infection and a quarter of them by three or more symptoms.
For each participant, clinical, virological, immunological,, serological and transcriptomics are collected in order to better characterize the disease. The objective is to accumulate knowledge on Covid-19, in particular on the most serious forms in order to improve care in cases where hospitalization is required. It is also about better understanding the future of patients in the short and long term by focusing on the possible in the months following the diagnosis.
What Are the Persistent Symptoms of Long Covid?
In their new study, the team describes the frequency and nature of persistent symptoms in 1,137 patients from French Covid, assessed during follow-up visits at 3 and 6 months after hospitalization for Covid-19. These studies suggest that 60% of patients are still affected by at least one symptom six months after infection and a quarter of them by three or more symptoms.
In addition, 2% of patients had to. A strong feeling of fatigue, breathing difficulties and muscle and joint were among the most frequently reported persistent clinical manifestations during these follow-up visits. A correlation between disease and long-term persistence of symptoms also appear to be emerging.
Women seem more at risk of suffering from symptoms that persist over time
Indeed, the persistence of at least 3 symptoms six months after infection is more frequent in people whose Covid-19 disease required a stay in intensive care compared to those who were hospitalized in a medical department, and in the most symptomatic patients on the day of admission to hospital. Researchers also observe gender differences: if men aresevere forms, women seem to be more at risk of suffering from persistent symptoms in the .
The difficult return to active life
The study finally underlines that these forms of ”Sometimes have wider consequences, both economically and socially. Thus, among the patients who report symptoms at 6 months and who were working when they were infected, a third did not return to work. To better understand the consequences of the virus on the body and the long-term impact of the disease, and above all to better manage patients, continuing this monitoring beyond 6 months in an even larger population could present a problem. certain interest.
« The mechanisms behind the persistence of symptoms as the body sheds the virus are still unclear. We will continue to monitor patients included in French Covid up to 18 months after infection, by also offering tests evaluating the», Underlines Jade Ghosn, cohort coordinator, PU-PH University of Paris and professor in the infectious and tropical diseases department of Bichat Claude-Bernard AP-HP Hospital.