Magnetic resonance imaging (MRT) data, which could be used as an individual measure of the loss of brain substance typical of Alzheimer’s disease, served as an indicator of the onset of Alzheimer’s disease. The treatment of periodontitis carried out by a dentist specializing in gum disease showed a positive effect on the loss of brain matter, which can be assessed as moderate to severe. The researchers used a recently developed statistical method that can simulate a controlled study. In doing so, available data from treated patients and untreated patients are brought together.
“Our approach is clearly in the prevention and timely treatment of gum disease, which can be triggered by a large number of germs, in order to prevent such possible consequential damage in advance,” emphasizes co-author Professor Thomas Kocher, Director of the Polyclinic for Dental Preservation, Periodontology, Endodontics, Pediatric Dentistry and Preventive Dentistry.
Periodontitis, the inflammation of the periodontium, is one of the most common chronic diseases worldwide. In Germany, too, around 11.5 million people suffer from a severe form of this widespread disease. Like an iceberg, the disease runs beneath the visible surface. And since it usually does not hurt either, it is often only recognized at a very advanced stage. So it is important to know warning signs of possible periodontal disease and to see the dentist at the first sign. Because early detection and systematic treatment can bring the disease process to a standstill.
Source: DOI: 10.1002 / alz.12378