The professor of the University of Castilla-La Mancha (UCLM) Ricardo Insausti has presented various publications of the project in which the UCLM collaborates with the University of Pennsylvania, whose objective is the early diagnosis of Alzheimer’s. Insausti has confirmed the progress in the tools “that serve as the basis for an early diagnosis of the disease”, as pointed out, in the course of a scientific conference, framed in the celebration of the XXV anniversary of the Association of Relatives and Patients of Alzheimer’s of Albacete (AFA).

Albacete Alzheimer's medicine

Albacete maintains the collaboration with Pennsylvania

The Faculty of Medicine of Albacete has hosted the scientific conference, organized by the Association of Relatives and Alzheimer’s Patients of Albacete (AFA), on the occasion of its 25th anniversary. During it, UCLM professor Ricardo Insausti released various publications on the project: “Specific changes of the medial temporal lobe in Alzheimer’s disease: Determination of new biomarkers by in vivo / ex vivo Neuroimaging”, in which UCLM works, through the Human Neuroanatomy Laboratory of the Albacete School of Medicine, and the University of Pennsylvania (Philadelphia, USA) in order to diagnose the disease early.

In his speech, Professor Insausti recalled the beginnings of the project, which date back to 2017, in which the Human Neuroanatomy Laboratory and the University of Pennsylvania (Philadelphia, USA) began to work together to combine the detailed study of the human hippocampus with advanced medical imaging techniques.

Publications in impact magazines

In the absence of a few months to complete the project, Insausti indicated that “progress has been made in the initial purpose of building tools that would serve as the basis for an early diagnosis of Alzheimer’s disease and other dementias.” He explained that in a group of more than 60 cases – from the UCLM brain and body donation program, and from autopsies performed at the University of Pennsylvania – three articles have been published to date in high-impact journals describing the methodology. and determination of the points in which the pathology is concentrated with defined patterns of the consequent cerebral atrophy.

Hippocampus and cerebral cortex

This methodology is offered in an open way for researchers, both clinical and basic, to address precise locations in the hippocampus and surrounding cerebral cortex in the study of memory and its alterations, present in Alzheimer’s disease and other dementias, as well as its characterization and use in the detection of changes in the brain in the preclinical phase of these neurodegenerative diseases.

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