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Impact of COVID on liver diseases and STIs

The pandemic has caused delays in the diagnosis and treatment of liver pathologies. It has also caused a decline in screening for sexually transmitted infections (STIs).

The collateral damage of COVID-19 A coronavirus disease, sometimes called covid (after the English acronym for coronavirus disease) is a disease caused by a coronavirus (CoV). The term can refer to the following diseases: Severe Acute Respiratory Syndrome (SARS) caused by the SARS-CoV virus, Middle East Respiratory Syndrome (MERS) caused by the MERS-CoV virus, Coronavirus disease 2019 (Covid-19 ) caused by the SARS-CoV-2 virus. on the management of liver diseases

The forecasts are not good. In the next ten years, delays in care related to COVID-19 could have serious consequences. The crisis focused all efforts on one pathology, to the detriment of others. According to mathematical models, the crisis could lead to 44,800 additional hepatocellular cancers and 72,300 liver-related deaths worldwide. A study conducted in the United States in 125 hospitals shows a drop in weekly hospitalizations for cirrhosis of 159% between the first quarter of 2019 and 2020. What patients who were admitted presented with much more severe cirrhosis. A worrying observation, confirmed by a French study carried out in six university hospitals in Île-de-France. This shows a decrease in the number of hospital admissions of patients with hepatocellular carcinoma, compared to the same period in 2019. In addition, treatment delays of more than a month were more frequent. In another article published in Journal of HepatologyElliott Tapper writes: “The COVID-19 pandemic has shattered the carefully crafted processes by which we provide quality care to patients with cirrhosis.”

an impact on HCV, HIV Human immunodeficiency virus. In English: HIV (Human Immunodeficiency Virus). Isolated in 1983 at the Pasteur Institute in Paris; recently discovered (2008) rewarded with the Nobel Prize in Medicine awarded to Luc Montagnier and Françoise Barré-Sinoussi. and the IS Sexually transmitted infections. bacteria

According to a survey conducted in 32 countries among civil society organizations involved in the fight against hepatitis C, the biggest problem was the decrease in testing during the first delivery in the spring of 2020. Liver diseases are not the only ones under the pandemic do not suffer This is also the case for STIs, such as HIV (Human Immunodeficiency Virus). Screening was particularly affected, with a decrease of 650,000 tests between January and September 2020.

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According to a study by UNAIDS (Joint United Nations Program on HIV/like Acquired immunodeficiency syndrome. In English, AIDS, acquired immuno-deficiency syndrome.), the impact of COVID-19 on production and logistics could significantly affect the supply of antiretroviral therapy worldwide. There is also a 20% drop in reports of chlamydia infections in the United States during the first ten months of 2020 compared to the same period in 2019. It is not known whether this is due to a decrease in transmission, or , more likely, to a drop in drug testing. In France, the same trend, with a significant drop of 60% in screening for bacterial STIs (syphilis, chlamydia, gonococcus) during the first delivery. But screening is essential. This allows patients to benefit from treatments and also to avoid the transmission of the disease.

Long-term effects

Some effects of the health crisis will take years to become visible. This has caused an economic crisis that can increase the consumption of alcohol and drugs, with adverse consequences for liver disease. So, the global survey Global drug survey, conducted between May and June 2020, shows an increase in the number of days of alcohol consumption in the general population. Efforts to reduce the collateral damage of COVID-19 will therefore need to continue in the long term. As Elliot Tapper points out, “Managing a serious chronic disease in the midst of a global infectious pandemic is a challenge. It is up to all health actors to be strong enough to weather the storm..

FR-VHCV-210177-07/2022

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