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Eyes tell you if you are at risk of an early death

Age can be an indicator of how long a person has left to live, but it doesn’t have to be. As Science Alert reports, a deep look into the eyes could be more revealing and that true biological age measure up.

Researchers have therefore taught a machine by analyzing the retina, the tissue at the back of the eye, “Fast-Ager‘ to identify those who are at increased risk of early death.

The one used for this algorithm can apparently determine this very precisely. He is said to be just under the biological age 47,000 adults middle-aged and older in the UK within a range of 3.5 years can predict.

Retina provides important insights

More than a decade after these retinas were scanned, are 1,871 people died and those whose retinas looked older were more likely to belong to this group.

For example, if the algorithm determined that a person’s retina was 1 year older than their actual age, their risk of dying from any cause over the next 11 years increased by 2 percent. The likelihood of dying from causes other than cardiovascular disease or cancer also increased by 3 percent.

Fundus camera image shows a right human eye with no evidence of disease. The gaze is directed into the camera so that the optic nerve head is in the direction of the nose (on the right in the picture).

The retina houses blood vessels and nerves and can therefore provide important information about the health of a person’s blood vessels and brain. Previous research has shown that the cells at the back of the human eye can help predict the onset of cardiovascular disease, kidney disease and other signs of aging.

Because it is pure observation data acts, it is not yet clear to what extent this factor is biologically related. However, it is the first study to use the “retinal age difference‘ as a powerful predictor of mortality. It also supports the increasing knowledge that the retina is very sensitive to age-related damage.

“The significant association between the retinal age gap and non-cardiovascular/non-cancer mortality, together with the increasing evidence of the eye-brain connection, may support the notion that the retina is the “Window” for neurological diseases is,” write the authors.

Methodology more precise and simple

Other existing predictors of biological age, such as neuroimaging, the DNA methylation clock, and the transcriptome aging clock, are not as accurate. These methods can also be costly, time-consuming, and invasive.

The retina, on the other hand, can 5 minutes be scanned. If more can be discovered about how this layer of tissue connects to the rest of the body, clinicians could have an excellent new tool in their hands.

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