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Antibodies against -synuclein without effect on the course of the disease

at Parkinson nerve cells die in the substantia nigra in the brain, leading to the typical symptoms of illness leads. Exactly why the neurons die is still unclear. »Previously it was assumed that α-synuclein deposits can cause the degenerative process, since the for the Illness typical Lewy bodies, round inclusions in the cytoplasm of nerve cells, consist of α-synuclein,” explains die German Society for Neurology (DGN) in a recent press release. »So there was great hope with α-synuclein-binding antibodies a causal one therapy against Parkinson’s disease. However, this hope was disappointed.«

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