An investigation of 25 experts from Argentina analyzed local data and managed to identify which people hospitalized for coronavirus were most affected by the disease, with the aim of evaluating and describing the clinical characteristics and factors associated with admission to intensive therapy and mortality.

“The main outcome of this analysis was mortality at 30 days from initial admission. The secondary outcome was admission to the intensive care unit (ICU) ”, the researchers explained in the results of the ECCOVID study, which was published in the prestigious international journal Plos One.

The study, which is an ongoing multicenter prospective observational cohort carried out in 19 medical centers of the AMBA and the interior of the country, where 809 patients were recruited between March and October 2020, was promoted and financed by the Research Commission of the Argentine Society of Infectology (SADI).

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The results

In the first place, in relation to the risk factors for going to intensive care, the specialists affirmed that the hypertension, obesity and diabetes are some comorbidities to consider.

“Those who had the most chances of entering the ICU are men, obese and hypertensive, among others,” he told Infobae one of the authors of the work, the infectologist Lautaro De Vedia, who highlighted the importance of “having local data”, given that “it is always better to confirm the situation of each place, see if there are any peculiarities”, although he clarified that “it is not what was seen in this work”. what .. here the same happened as in the rest of the countries.

“Regarding mortality, we saw an increased risk in those over 60 years of age and in those who required oxygen,” he said. Ezequiel Córdova, Argerich doctor, member of SADI and another of the study authors.

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According to the research data, the average age of the internees was 53 years: 56% were male and 71% had at least one comorbidity, most frequently it was due to hypertension (32%), obesity (23%) and diabetes (17%). The severity of the disease on admission was classified as mild 25%, moderate 51%, severe 17%, and critical 7%.

In addition, the 18% of patients had to go to intensive care and 12% of the total had to use a respirator. Regarding global mortality, at 30 days it was 11%, although it reached 36% among those who entered therapy and 50% among those who required mechanical ventilation, and according to the researchers, “the factors independently associated with 30-day mortality included age older than 60 years and oxygen saturation less than 93%.

Finally, the scientists highlighted that “the most frequent symptoms reported before or upon admission were fever (61%), tos (60%) and dyspnoea (40%) ”, and that, upon admission, almost a third of the patients (30%) had an abnormal body temperature greater than 37.5 ° C and 18.5% had a fever (more than 38 ° C). Likewise, the average time from the onset of symptoms to hospitalization was five days.

Although the published results are from the first wave in our country, the study continued and the experts are analyzing the data from the second wave, where they will seek to analyze if the risk factors are repeated and if the new strains modified the results.


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